Cytosolic phospholipase A2: biochemical properties and physiological roles.

@article{Shimizu2006CytosolicPA,
  title={Cytosolic phospholipase A2: biochemical properties and physiological roles.},
  author={Takao Shimizu and Takayo Ohto and Yoshihiro Kita},
  journal={IUBMB life},
  year={2006},
  volume={58 5-6},
  pages={328-33}
}
Phosphatidylcholine (PC) is a major constituent of biological membranes and a component of serum lipoproteins and pulmonary surfactants. The PC and other glycerophospholipid compositions of membranes change dynamically through stimulus-dependent and independent pathways, principally by the action of two different types of enzymes; phospholipase A2 [EC 3.1.1.4] and acyl-CoA:lysophospholipid acyltransferase [EC 2.3.1.23]. Phospholipase A2 is a key enzyme that catalyzes deacylation of the sn-2… CONTINUE READING