Cytosolic calreticulin inhibits microwave radiation-induced microvascular endothelial cell injury through the integrin-focal adhesion kinase pathway.

@article{Xu2014CytosolicCI,
  title={Cytosolic calreticulin inhibits microwave radiation-induced microvascular endothelial cell injury through the integrin-focal adhesion kinase pathway.},
  author={Fei-Fei Xu and Tian-Qi Tao and Xiao-Reng Wang and Yu-zhen Li and Dandan Song and Mi Liu and XiuHua Liu},
  journal={Microcirculation},
  year={2014},
  volume={21 8},
  pages={717-29}
}
OBJECTIVE To determine the effects of cytosolic CRT on MR-induced MMEC injury, and the underlying mechanism. METHODS MMECs were randomized into eight groups: control, AdCRT (infected with pAdCMV/V5-DEST-CRT adenovirus), stCRT (transfected with rCRT-siRNAs), Mock (transfected with scrambled siRNAs), MR (exposed to MR for six minutes), AdCRT + MR, stCRT + MR, and Mock + MR. The magnitude of cell injury were assessed by Annexin V-PI staining, LDH activity in culture medium, MMEC migration… CONTINUE READING