Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin.

  title={Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin.},
  author={Andrew Oleinikov and J D Zhao and Sudesh Paul Makker},
  journal={The Biochemical journal},
  volume={347 Pt 3},
gp600/megalin, an endocytic receptor, belongs to the low-density lipoprotein receptor family. It is most abundant in the renal proximal tubular cells, where it is implicated in the reabsorption of a number of molecules filtered through the glomerulus. The cytoplasmic tail (CT) of gp600/megalin contains a number of sequence similarities, which indicate that gp600/megalin might be involved in signal transduction. To find intracellular proteins that would interact with the gp600/megalin CT, a… 
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