Cytosol as battleground: ubiquitin as a weapon for both host and pathogen.

@article{Collins2010CytosolAB,
  title={Cytosol as battleground: ubiquitin as a weapon for both host and pathogen.},
  author={Cathleen A. Collins and Eric J. Brown},
  journal={Trends in cell biology},
  year={2010},
  volume={20 4},
  pages={205-13}
}
Ubiquitin was first described as a tag allowing cells to degrade and recycle their own proteins. Recent research has shown ubiquitin to be central for immune system recognition of invading bacteria. This review describes a set of complex host-pathogen interactions that are dependent on ubiquitination. From the host perspective, ubiquitin-dependent… CONTINUE READING