Cytoskeleton: Filopodia self-assemble

Filopodia are finger-like projections made up of bundled actin filaments that have many biological roles, including cell migration. How filopodia are formed has been difficult to determine, as current experimental systems do not recapitulate aspects of filopodium biology. Kirschner and colleagues now address this question using an in vitro model system in… CONTINUE READING