Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines.

Abstract

The tight junction (TJ) is a specialized intercellular structure responsible for the regulation of ionic and macromolecular flux across cell monolayers. Because plasma leakage is believed to occur mainly across the microvasculature, we hypothesized that microvascular endothelial cells (MVEC) may form more intact, regulatable TJ than other endothelial cell… (More)

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@article{Blum1997CytoskeletalRM, title={Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines.}, author={Murray S. Blum and Elena Toninelli and J. M. Anderson and Maria Susana Balda and J. Zhou and Lauren A O'Donnell and Ravindra L. Pardi and Jan Bender}, journal={The American journal of physiology}, year={1997}, volume={273 1 Pt 2}, pages={H286-94} }