Cytoskeletal rearrangement and cell death induced by Bothrops alternatus snake venom in cultured Madin-Darby canine kidney cells.

@article{Nascimento2007CytoskeletalRA,
  title={Cytoskeletal rearrangement and cell death induced by Bothrops alternatus snake venom in cultured Madin-Darby canine kidney cells.},
  author={Juliana M. Nascimento and Gilberto Carlos Franchi and Alexandre Eduardo Nowill and Carla Beatriz Collares-Buzato and Stephen Hyslop},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2007},
  volume={85 5},
  pages={591-605}
}
Bothrops snake venoms cause renal damage, with renal failure being the main cause of death in humans bitten by these snakes. In this work, we investigated the cytoskeletal rearrangement and cytotoxicity caused by Bothrops alternatus venom in cultured Madin-Darby canine kidney (MDCK) cells. Incubation with venom (10 and 100 microg/mL) significantly (p <0.05) decreased the cellular uptake of neutral red dye after 1 and 3 h. Venom (100 microg/mL) also markedly decreased the transepithelial… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…