Although the structure of cross-linking molecules mainly determines the structural organization of actin filaments and with that the static elastic properties of the cytoskeleton, it is largely unknown how the biochemical characteristics of transiently cross-linking proteins (actin-binding proteins (ABPs)) affect the viscoelasticity of actin networks. In… (More)
FIGURE 6 Fitting parameters for prestressed actin/HMM networks as obtained for the data sets depicted in Fig. 5, A and B. (A) Enhancement of the network elasticity G0/G0(s0 ¼ 0) as a function of prestress s0. A linear relation is observed for both cross-linker densities (R ¼ 0.1 (squares) and R ¼ 0.2 (crosses)). (B) Stress relaxation parameter c and single filament relaxation parameter d increase linear with the prestress s0. (C) Cross-linker off-rate koff as a function of prestress for two different actin/HMM networks (R ¼ 0.1 ( ) and R ¼ 0.2 (þ)).