Cytoskeletal modulation of electrical and mechanical activity in cardiac myocytes.

@article{Calaghan2004CytoskeletalMO,
  title={Cytoskeletal modulation of electrical and mechanical activity in cardiac myocytes.},
  author={Sarah C Calaghan and J-Y Le Guennec and Ed White},
  journal={Progress in biophysics and molecular biology},
  year={2004},
  volume={84 1},
  pages={29-59}
}
The cardiac myocyte has an intracellular scaffold, the cytoskeleton, which has been implicated in several cardiac pathologies including hypertrophy and failure. In this review we describe the role that the cytoskeleton plays in modulating both the electrical activity (through ion channels and exchangers) and mechanical (or contractile) activity of the adult… CONTINUE READING