Cytoreductive surgery and adjuvant immunotherapy: a new management paradigm for metastatic melanoma.

@article{Morton1999CytoreductiveSA,
  title={Cytoreductive surgery and adjuvant immunotherapy: a new management paradigm for metastatic melanoma.},
  author={Donald L. Morton and David W. Ollila and Eddy C. Hsueh and Richard Essner and Rishab K. Gupta},
  journal={CA: a cancer journal for clinicians},
  year={1999},
  volume={49 2},
  pages={101-16, 65}
}
Although patients with metastatic disease are usually not offered surgery as part of their comprehensive treatment plan, the authors suggest that surgical reduction of the tumor burden may enhance the host immune response and create a favorable setting for the use of active specific immunotherapy. 

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