Cytoreductive nephrectomy for kidney cancer with sarcomatoid histology--is up-front resection indicated and, if not, is it avoidable?

@article{Shuch2009CytoreductiveNF,
  title={Cytoreductive nephrectomy for kidney cancer with sarcomatoid histology--is up-front resection indicated and, if not, is it avoidable?},
  author={Brian Shuch and Jonathan Said and Jeff C La Rochelle and Ying Zhou and Gang Li and Tobias Klatte and Fairooz F Kabbinaavar and Allan J. Pantuck and Arie S. Belldegrun},
  journal={The Journal of urology},
  year={2009},
  volume={182 5},
  pages={2164-71}
}
PURPOSE Cytoreductive nephrectomy has a survival advantage in select patients. Patients with sarcomatoid features are known to have poor outcomes. We reviewed the role of surgery in this population to see if these patients could be identified preoperatively. MATERIALS AND METHODS Cytoreductive nephrectomy cases identified as having sarcomatoid features or spindle cells were reviewed. The histology, grade, and the presence and percentage of sarcomatoid elements were recorded… CONTINUE READING

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