Cytoprotective effects of 5 benzophenones and a xanthone from Hypericum annulatum in models of epirubicin-induced cytotoxicity: SAR-analysis and mechanistic investigations.

@article{Momekov2006CytoprotectiveEO,
  title={Cytoprotective effects of 5 benzophenones and a xanthone from Hypericum annulatum in models of epirubicin-induced cytotoxicity: SAR-analysis and mechanistic investigations.},
  author={G. Momekov and P. Nedialkov and G. Kitanov and Dimitrina Zh Zheleva-Dimitrova and Tzvetomira Tzanova and U. Girreser and M. Karaivanova},
  journal={Medicinal chemistry (Shariqah (United Arab Emirates))},
  year={2006},
  volume={2 4},
  pages={
          377-84
        }
}
  • G. Momekov, P. Nedialkov, +4 authors M. Karaivanova
  • Published 2006
  • Chemistry, Medicine
  • Medicinal chemistry (Shariqah (United Arab Emirates))
  • A new benzophenone O-glucoside neoannulatophenonoside (1) together with the known pinocembrin-7-O-glucoside were isolated from the aerial parts of Hyperium annulatum Moris (Guttiferae). The former was identified as 3',5',6-trihydroxy-4-methoxybenzophenone-2-O-beta-D-glucopyranoside by means of chemical and physical evidence. The cytoprotective effects of the new compound together with the previously isolated from this species hypericophenonoside (2), annulatophenone (3), annulatophenonoside (4… CONTINUE READING
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