Cytoplasmic poly(A) binding protein C4 serves a critical role in erythroid differentiation.

Abstract

The expression of an mRNA is strongly impacted by its 3' poly(A) tail and associated poly(A)-binding proteins (PABPs). Vertebrates encode six PABP isoforms that vary in abundance, distribution, developmental control, and subcellular localization. Here we demonstrate that the minor PABP isoform PABPC4 is expressed in erythroid cells and impacts the steady… (More)
DOI: 10.1128/MCB.01683-13

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