Cytoplasmic expression of SSTR2 and 5 by immunohistochemistry and by RT/PCR is not associated with the pharmacological response to octreotide.

Abstract

OBJECTIVE To evaluate expression of somatostatin receptor subtypes 2 and 5 (SSTR 2 and 5) by RT/PCR and immunohistochemistry (IHC) in GH-secreting adenomas, seeking correlations with response to octreotide. METHODS SSTR2 and 5 expression was tested by IHC (n=37), RT/PCR (n=36) or both (n=13) in GH-secreting adenomas from 60 patients with acromegaly who… (More)
DOI: 10.1016/j.endonu.2014.05.006

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@article{Gonzalez2014CytoplasmicEO, title={Cytoplasmic expression of SSTR2 and 5 by immunohistochemistry and by RT/PCR is not associated with the pharmacological response to octreotide.}, author={Baldomero Gonzalez and Guadalupe Vargas and Claudia Ximena Ram{\'i}rez and Silvia Asa and Sonia Wing Mei Cheng and C. I. Villeda - Sandoval and Mois{\'e}s Mercado}, journal={Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion}, year={2014}, volume={61 10}, pages={523-30} }