Cytoplasmic domain of E-selectin contains a non-tyrosine endocytosis signal.

Abstract

E-selectin is an activation-dependent, endothelial cell-restricted adhesion molecule that is internalized and degraded rapidly once expressed on the cell surface. Tyrosine-containing structural motifs play an important role in the internalization of a number of integral proteins, and the membrane-proximal E-selectin cytoplasmic tyrosine residue (Tyr582… (More)

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Cite this paper

@article{Chuang1997CytoplasmicDO, title={Cytoplasmic domain of E-selectin contains a non-tyrosine endocytosis signal.}, author={Peter I Chuang and Bradford A. Young and Ravi R. Thiagarajan and Carol J Cornejo and Robert K. Winn and John Marshall Harlan}, journal={The Journal of biological chemistry}, year={1997}, volume={272 40}, pages={24813-8} }