Cytoplasmic Acidification and the Benzoate Transcriptome in Bacillus subtilis

@inproceedings{Kitko2009CytoplasmicAA,
  title={Cytoplasmic Acidification and the Benzoate Transcriptome in Bacillus subtilis},
  author={Ryan D. Kitko and Rebecca L. Cleeton and Erin I. Armentrout and Grace E. Lee and Ken Ichi Noguchi and Melanie B. Berkmen and Brian D. Jones and Joan L. Slonczewski},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND Bacillus subtilis encounters a wide range of environmental pH. The bacteria maintain cytoplasmic pH within a narrow range. Response to acid stress is a poorly understood function of external pH and of permeant acids that conduct protons into the cytoplasm. METHODS AND PRINCIPAL FINDINGS Cytoplasmic acidification and the benzoate transcriptome were observed in Bacillus subtilis. Cytoplasmic pH was measured with 4-s time resolution using GFPmut3b fluorimetry. Rapid external… CONTINUE READING

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