Cytopathological diagnosis of adult retinoblastoma in a vitrectomy specimen.

  title={Cytopathological diagnosis of adult retinoblastoma in a vitrectomy specimen.},
  author={Mar{\'i}a Eugenia Orellana and Fadi Brimo and Manon Auger and John Galic and Jean L Desch{\^e}nes and Miguel Noel Burnier},
  journal={Diagnostic cytopathology},
  volume={38 1},
Retinoblastoma (RB) is extremely rare in adults. We describe a case of RB diagnosed by cytology in a vitrectomy specimen of a 23-year-old patient who presented with diminished visual acuity and retinal detachment in the absence of a clinically-visible mass. Cytological examination of the vitreous fluid showed clusters of loosely cohesive atypical cells with high nuclear to cytoplasmic ratio and "salt and pepper" chromatin pattern in a background of normal neuronal retinal cells. Nuclear molding… CONTINUE READING

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