Cytopathogenic Effects of Herpes Simplex Virus on Corneal Epithelium

  title={Cytopathogenic Effects of Herpes Simplex Virus on Corneal Epithelium},
  author={P. C. Maudgal and Luc Missotten},
Histopathological and cytological changes in the experimental herpes simplex virus (HSV-1) keratitis and dendritic corneal ulcers in patients was studied by using the in vivo corneal replica technique1-3. To make a corneal replica a topical anesthetic is instilled thrice into the eye at five minutes intervals. The eyelids are separated by an ocular speculum. Corneal surface is dried by blowing air for about one minute. An airpump used in fish-tanks is suitable for this purpose. Collodion… CONTINUE READING