Cytomegalovirus microRNAs Facilitate Persistent Virus Infection in Salivary Glands

@inproceedings{Dlken2010CytomegalovirusMF,
  title={Cytomegalovirus microRNAs Facilitate Persistent Virus Infection in Salivary Glands},
  author={Lars D{\"o}lken and Astrid Krmpotic and Sheila Kothe and Lee Tuddenham and M{\'e}lanie Tanguy and Lisa Marcinowski and Zsolt Ruzsics and Naama Elefant and Yael Altuvia and Hanah Margalit and Ulrich Koszinowski and Stipan Jonji{\'c} and S{\'e}bastien Pfeffer},
  booktitle={PLoS pathogens},
  year={2010}
}
Micro (mi)RNAs are small non-coding RNAs that regulate the expression of their targets' messenger RNAs through both translational inhibition and regulation of target RNA stability. Recently, a number of viruses, particularly of the herpesvirus family, have been shown to express their own miRNAs to control both viral and cellular transcripts. Although some targets of viral miRNAs are known, their function in a physiologically relevant infection remains to be elucidated. As such, no in vivo… CONTINUE READING

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