Cytomegalovirus maculopapular eruption in a kidney transplant patient.

Abstract

Cytomegalovirus (CMV) is the most important viral agent in kidney transplantation. Clinical manifestations of CMV disease in transplantation include hepatitis, pneumonitis, pancreatitis, kidney allograft dysfunction, colitis, and meningoencephalitis. However, skin involvement is rare. We describe a severely compromised cadaveric-kidney transplant recipient who developed renal failure, colonic ulcers, and a maculopapular rash accompanied by fever and malaise 4 months after transplantation. Only the skin biopsy was diagnostic and consistent with CMV disease. Intravenous ganciclovir administration resulted in clinical improvement of CMV-induced skin lesions; kidney function normalized and the patient became asymptomatic after 14 days of ganciclovir therapy. Nephrologists should consider the diagnosis of CMV disease in the febrile immunosuppressed patient with skin involvement. Skin biopsy must be considered as a useful and safe procedure in patients with a rash to obtain a prompt diagnosis and efficiently treat this immunocompromised population.

Statistics

0102030'03'05'07'09'11'13'15'17
Citations per Year

58 Citations

Semantic Scholar estimates that this publication has 58 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Trimarchi2001CytomegalovirusME, title={Cytomegalovirus maculopapular eruption in a kidney transplant patient.}, author={Hern{\'a}n Trimarchi and Guillermo Casas and Roberto Jordan and J V Mart{\'i}nez and Juan Schropp and Emilio Freixas and E D Efron}, journal={Transplant infectious disease : an official journal of the Transplantation Society}, year={2001}, volume={3 1}, pages={47-50} }