Cytomegalovirus infection enhances the immune response to influenza

  title={Cytomegalovirus infection enhances the immune response to influenza},
  author={David Furman and Vladimir Jojic and Shalini Sharma and Shai S. Shen-Orr and Cesar Joel Lopez Angel and Suna Onengut-Gumuscu and Brian A. Kidd and Holden T. Maecker and Patrick Concannon and Cornelia L Dekker and Paul G. Thomas and Mark M. Davis},
  journal={Science Translational Medicine},
Cytomegalovirus (CMV) is a β-herpesvirus present in a latent form in most people worldwide. In immunosuppressed individuals, CMV can reactivate and cause serious clinical complications, but the effect of the latent state on healthy people remains elusive. We undertook a systems approach to understand the differences between seropositive and negative subjects and measured hundreds of immune system components from blood samples including cytokines and chemokines, immune cell phenotyping, gene… CONTINUE READING
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