Cytomegalovirus antigen within human arterial smooth muscle cells.

  title={Cytomegalovirus antigen within human arterial smooth muscle cells.},
  author={Joseph L. Melnick and B L Petrie and Gordon R. Dreesman and Joyce Burek and Charles H. McCollum and Michael E Debakey},
  volume={2 8351},
Arterial tissues from carotid artery plaques or from punch-biopsy samples of uninvolved areas of the aorta were removed from 132 patients with atherosclerosis during blood-vessel surgery. Cells morphologically identical to smooth muscle cells were cultured from 26 to 126 plaque samples and from 6 of 6 punch-biopsy samples. Immunofluorescence tests of these cells showed that more than 25% of the cell cultures from both types of sample contained antigens of human cytomegalovirus (CMV) but not of… CONTINUE READING


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