Cytological mapping of human X-linked genes by use of somatic cell hybrids involving an X-autosome translocation (mouse-hamster-human X-linked markers).

@article{Grzeschik1972CytologicalMO,
  title={Cytological mapping of human X-linked genes by use of somatic cell hybrids involving an X-autosome translocation (mouse-hamster-human X-linked markers).},
  author={K. H. Grzeschik and Penelope W Allderdice and A Grzeschik and John M Opitz and Orlando J. Miller and Marcello Siniscalco},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1972},
  volume={69 1},
  pages={
          69-73
        }
}
  • K. H. Grzeschik, Penelope W Allderdice, +3 authors Marcello Siniscalco
  • Published in
    Proceedings of the National…
    1972
  • Biology, Medicine
  • Man-mouse and man-Syrian hamster somatic hybrid cell lines were prepared by fusion of mouse A9 or hamster TG2 cells, which are deficient in hypoxanthine-guanine phosphoribosyl transferase, with cells of a diploid fibroblastic strain, KOP-1, derived from a woman heterozygous for an X-autosome translocation. 61 clones were derived in nonselective medium and 85 sublines of these were derived in selective media: 53 in hypoxanthine-aminopterine-thymidine and 32 in 8-azaguanine. All three human X… CONTINUE READING

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    Nature of mutations conferring resistance to 8-azaguanine in mouse cell lines.

    • S I Shin
    • Biology, Medicine
    • Journal of cell science
    • 1974
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