Cytological detection of mutagen–carcinogen exposure by sister chromatid exchange

@article{Perry1975CytologicalDO,
  title={Cytological detection of mutagen–carcinogen exposure by sister chromatid exchange},
  author={P. Perry and H. Evans},
  journal={Nature},
  year={1975},
  volume={258},
  pages={121-125}
}
A staining technique that detects sister chromatid exchanges (SCEs) has been used to examine the response of chromosomes in cultured Chinese hamster cells to a wide variety of mutagens–carcinogens. The test gives a very sensitive and rapid method for detecting chromosome mutagenicity of chemical agents and provides a powerful new method for detecting environmental mutagens. 

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