Cytological and molecular diagnosis of solid variant of papillary thyroid carcinoma: A case report

@article{Troncone2008CytologicalAM,
  title={Cytological and molecular diagnosis of solid variant of papillary thyroid carcinoma: A case report},
  author={Giancarlo Troncone and Maria Elena Russo and Umberto Malapelle and Marina Accardo and Angelo Ferraro and Immacolata Cozzolino and Lucio Palombini},
  journal={CytoJournal},
  year={2008},
  volume={5},
  pages={2 - 2}
}
Papillary thyroid carcinoma (PTC) composed by predominant solid areas is diagnosed as a distinct variant on histological samples. Here we present a case of PTC recognized preoperatively by fine needle cytology as a solid variant. This diagnosis was made by combining cytology with the detection of the BRAFVK600-1E mutation, the molecular hallmark of the solid variant of PTC. Histological and molecular evaluation of the surgical specimen confirmed this pre-operative diagnosis. Thus combining… CONTINUE READING

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