• DOI:10.1016/j.cyto.2017.04.013
Corpus ID: 3568330

Cytokines in the management of rotavirus infection: A systematic review of in vivo studies

@article{Gandhi2017CytokinesIT,
  title={Cytokines in the management of rotavirus infection: A systematic review of in vivo studies},
  author={G. R. Gandhi and V. Santos and Marina Denadai and Valdete Kaliane da Silva Calisto and J. de Souza Siqueira Quintans and A. M. de Oliveira e Silva and A. A. de Souza Ara{\'u}jo and N. Narain and L. Cuevas and L. J{\'u}nior and R. Gurgel},
  journal={Cytokine},
  year={2017},
  volume={96},
  pages={152–160}
}

G. R. Gandhi, V. Santos, +8 authors R. Gurgel

Published 2017

Biology, Medicine

Cytokine

Objective Rotavirus is a leading cause of childhood diarrhoea. Rotavirus vaccines are effective against severe rotavirus gastroenteritis, but have lower efficacy in low income countries in Africa. Anti‐rotavirus treatment is not available. This study reviews the literature of animal studies evaluating whether cytokine mediated pathways of immune activation could improve rotavirus therapy. Methods We performed a systematic review of articles in English published from 2010 to 2016 reporting… CONTINUE READING

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