Cytokines in neuroinflammation and Alzheimer's disease.

  title={Cytokines in neuroinflammation and Alzheimer's disease.},
  author={Mathias Cacquevel and Nathalie Lebeurrier and Simon Ch{\'e}enne and Denis Vivien},
  journal={Current drug targets},
  volume={5 6},
Inflammation has been reported in numerous neurodegenerative disorders such as Parkinson's disease, stroke and Alzheimer's disease (AD). In AD, the inflammatory response is mainly located to the vicinity of amyloid plaques. Cytokines, such as Interleukin-1 (IL-1), Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha) and Transforminng Growth Factor beta (TGF-beta) have been clearly involved in this inflammatory process. Although their expression is induced by the presence of amyloid… CONTINUE READING