Cytokines in cancer drug resistance: Cues to new therapeutic strategies.

  title={Cytokines in cancer drug resistance: Cues to new therapeutic strategies.},
  author={Valerie Sloane Jones and Ren-Yu Huang and Li-pai Chen and Zhe-Sheng Chen and Liwu Fu and Ruopan Huang},
  journal={Biochimica et biophysica acta},
  volume={1865 2},
The development of oncoprotein-targeted anticancer drugs is an invaluable weapon in the war against cancer. However, cancers do not give up without a fight. They may develop multiple mechanisms of drug resistance, including apoptosis inhibition, drug expulsion, and increased proliferation that reduce the effectiveness of the drug. The collective work of researchers has highlighted the role of cytokines in the mechanisms of cancer drug resistance, as well as in cancer cell progression… CONTINUE READING
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