Cytokines genes polymorphisms in chronic hepatitis C: impact on susceptibility to infection and response to therapy.

@article{Pasha2013CytokinesGP,
  title={Cytokines genes polymorphisms in chronic hepatitis C: impact on susceptibility to infection and response to therapy.},
  author={Heba Fouad Pasha and Mohamed I Radwan and Hoda A. Hagrass and Enas A. Tantawy and Mohamed H Emara},
  journal={Cytokine},
  year={2013},
  volume={61 2},
  pages={478-84}
}
BACKGROUND Cytokines play a key role in the regulation of immune responses. In hepatitis C virus infection, the production of abnormal cytokine levels appears to contribute in the progression of the disease, viral persistence, and affects response to therapy. Cytokine genes polymorphisms located within the coding/regulatory regions have been shown to affect the overall expression and secretion of cytokines. The aim of the study was to evaluate the association of of IL28B rs12979860, TGF-β1-509… CONTINUE READING

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