Cytokines for surgeons.

  title={Cytokines for surgeons.},
  author={Christopher D. Raeburn and Forest Sheppard and Katherine A. Barsness and Jyoti Arya and Alden Hood Harken},
  journal={American journal of surgery},
  volume={183 3},
All cells maintain continuous communication. Hormones derive constitutively from specialized cells to effect total body homeostasis. Conversely, cytokines are produced sporadically from almost all nucleated cells in response to surgical ischemia/septic challenge. Surgical patients are a stew of pulsating cytokines, which serve as the language between all surgically stressed somatic and myeloid cells. Therapeutic manipulation of cytokines has already generated some exhilarating success stories… CONTINUE READING