Cytokines as predictive biomarkers of alloreactivity.

@article{Brunet2012CytokinesAP,
  title={Cytokines as predictive biomarkers of alloreactivity.},
  author={Merce M Brunet},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2012},
  volume={413 17-18},
  pages={
          1354-8
        }
}
Clinical use of valid biomarkers enables the prediction of alloreactive response (risk of rejection) and personal susceptibility to immunosuppressive treatment could lead to personalized immunosuppressive therapy. In clinical transplantation, it has been reported that cytokine production and secretion could be modified by immunosuppressive drugs, as well as during the rejection process. Some cytokines such as interferon (IFN)-γ, interleukin (IL)-2, IL-10, and transforming growth factor (TGF… CONTINUE READING
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