Cytokines and growth factors involved in apoptosis and proliferation of vascular smooth muscle cells.

@article{Rakesh2005CytokinesAG,
  title={Cytokines and growth factors involved in apoptosis and proliferation of vascular smooth muscle cells.},
  author={Kriti Rakesh and Devendra K Agrawal},
  journal={International immunopharmacology},
  year={2005},
  volume={5 10},
  pages={1487-506}
}
This review focuses on the role of cytokines and growth factors involved in the regulation of smooth muscle cells in an atherosclerotic plaque. As a plaque begins to develop, upon endothelial injury inflammatory cells within the lesion interact with the accumulating LDL, other inflammatory cells and smooth muscle cells and release cytokines and growth factors. The mediators released from the activated cells regulate the proliferation and/or survival of smooth muscle cells. This determines the… CONTINUE READING

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