Cytokines and atherosclerosis: a comprehensive review of studies in mice

@article{Kleemann2008CytokinesAA,
  title={Cytokines and atherosclerosis: a comprehensive review of studies in mice},
  author={Robert Kleemann and Susanne M. Zadelaar and Teake Kooistra},
  journal={Cardiovascular Research},
  year={2008},
  volume={79},
  pages={360 - 376}
}
In the past few years, inflammation has emerged as a major driving force of atherosclerotic lesion development. It is now well-established that from early lesion to vulnerable plaque formation, numerous cellular and molecular inflammatory components participate in the disease process. The most prominent cells that invade in evolving lesions are monocyte-derived macrophages and T-lymphocytes. Both cell types produce a wide array of soluble inflammatory mediators (cytokines, chemokines) which are… CONTINUE READING
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