Cytokines and anticytokines in psoriasis.

  title={Cytokines and anticytokines in psoriasis.},
  author={Aldona Pietrzak and Anna Zalewska and Grażyna Chodorowska and Dorota Krasowska and Anna Michalak-Stoma and Piotr Nockowski and Paweł Osemlak and Tomasz Paszkowski and Jacek Roliński},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={394 1-2},
BACKGROUND Psoriasis is a chronic autoimmune hyperproliferative skin disease of varying severity affecting approximately 2-3% of the general population in the USA and Europe. Although the pathogenesis of psoriasis has not been fully elucidated, an immunologic-genetic relationship is likely. Cutaneous and systemic overexpression of various proinflammatory cytokines (TNF, interleukins, interferon-gamma) has been demonstrated in psoriatic patients. METHODS We reviewed the current database… CONTINUE READING

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