Cytokines: T cells take a break from IL-7

  title={Cytokines: T cells take a break from IL-7},
  author={Yvonne Bordon},
  journal={Nature Reviews Immunology},
  • Yvonne Bordon
  • Published 1 February 2013
  • Biology
  • Nature Reviews Immunology


IL-7 signaling must be intermittent, not continuous, during CD8 T cell homeostasis to promote cell survival instead of cell death

Regulation of the duration of IL-7 signaling by homeostatic engagement of the TCR as the basis for in vivo CD8+ T cell homeostasis is identified.