Cytokine therapies in HIV-1 infection: present and future.

  title={Cytokine therapies in HIV-1 infection: present and future.},
  author={Sarah L. Pett and Anthony D. Kelleher},
  journal={Expert review of anti-infective therapy},
  volume={1 1},
Since the introduction of highly active antiretroviral therapy (HAART), HIV-related deaths have declined dramatically in the developed world. However, HAART is neither able to eradicate the virus nor are its immunomodulatory effects sufficient to effect complete control of the virus. In addition, the long-term use of HAART is complicated by drug-related toxicities and compliance issues, both of which impact upon the development of viral resistance. The failure of structured treatment… CONTINUE READING