Cytokine storm in acute pancreatitis.

  title={Cytokine storm in acute pancreatitis.},
  author={Rohit Makhija and A. Kingsnorth},
  journal={Journal of hepato-biliary-pancreatic surgery},
  volume={9 4},
Efforts to unravel the events in the evolution of tissue damage in acute pancreatitis have shown a number of inflammatory mediators to be involved. The pathways of damage are similar, whatever the etiology of pancreatitis, with three phases of progression: local acinar injury, systemic response, and generalized sepsis. The proinflammatory response is countered by an anti-inflammatory response, and an imbalance between these two systems leads to localized tissue destruction and distant organ… CONTINUE READING


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