Cytokine signaling exposed.

Abstract

In this issue, Lupardus et al. (2011) provide images, obtained by electron microscopy, of a complete cytokine signaling complex, offering clues into the mechanism by which binding of cytokines to their cognate receptors triggers trans-phosphorylation and activation of Janus kinases. 
DOI: 10.1016/j.str.2010.12.010

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