Cytokine receptors and signal transduction.

  title={Cytokine receptors and signal transduction.},
  author={Alice L.-F. Mui and Atsushi Miyajima},
  journal={Progress in growth factor research},
  volume={5 1},
Cytokines are important regulators of hemopoiesis which exert their actions by binding to specific, high affinity, cell surface receptors. In the past several years, molecular cloning of these receptors has revealed a new superfamily referred to as the hemopoietic growth factor receptors. Members of this family are defined by a 200 amino acid conserved domain; however, it has become increasingly apparent that another characteristic of these receptors is the shared usage of a common signalling… CONTINUE READING


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