Cytokine promoter polymorphisms and risk of colorectal cancer.

@article{Burada2013CytokinePP,
  title={Cytokine promoter polymorphisms and risk of colorectal cancer.},
  author={Florin Burada and Theodor Dumitrescu and Raluca Nicoli and Marius Eugen Ciurea and Ion Rogoveanu and Mihai Ioana},
  journal={Clinical laboratory},
  year={2013},
  volume={59 7-8},
  pages={
          773-9
        }
}
BACKGROUND Cytokines and chemokines are involved in cancer development and progression, but their role in colorectal tumorigenesis is still far from well defined. This study investigated the association between five cytokine promoter polymorphisms and risk, stage, and histological grade of colorectal cancer (CRC) in a hospital-based case-control study. METHODS A total of 377 Romanian subjects were included in this study: 144 patients with sporadic colorectal cancer and 233 controls. Cytokine… CONTINUE READING

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