Cytokine profiles in tuberculosis patients and healthy subjects in response to complex and single antigens of Mycobacterium tuberculosis.

@article{AlAttiyah2006CytokinePI,
  title={Cytokine profiles in tuberculosis patients and healthy subjects in response to complex and single antigens of Mycobacterium tuberculosis.},
  author={Rajaa J. Al-Attiyah and Nadam Madi and Abdul-Salaamm El-Shamy and Haraldg Wiker and Peter Hvilsh\oj Andersen and Abus Mustafa},
  journal={FEMS immunology and medical microbiology},
  year={2006},
  volume={47 2},
  pages={254-61}
}
Peripheral blood mononuclear cells (PBMC) were obtained from tuberculosis (TB) patients and Mycobacterium bovis bacillus Calmette-Guerin vaccinated healthy subjects. PBMC were tested for secretion of tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-5 (IL-5) and IL-10 in response to complex (whole cells, culture filtrate and cell walls), single secreted (Ag85B, ESAT6, MPT64, PstS and MPT70) and single cytosolic (DnaK, GroES and GroEL) antigens of Mycobacterium… CONTINUE READING