Cytokine production in the central nervous system.

  title={Cytokine production in the central nervous system.},
  author={M. Nicola Woodroofe},
  volume={45 6 Suppl 6},
Cytokines participate in normal physiologic events within the CNS. At times of infection and inflammation, their role is emphasized by the upregulation of cytokines and their receptors within the CNS, with concomitant effects on brain function. Cytokines produced by glial cells, T cells, and macrophages interact within the CNS to determine the outcome of the inflammatory reaction. Cytokines have been implicated in the pathogenesis of many CNS diseases, including multiple sclerosis (MS), and… CONTINUE READING

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