Cytokine production in bipolar affective disorder patients under lithium treatment.

@article{Boufidou2004CytokinePI,
  title={Cytokine production in bipolar affective disorder patients under lithium treatment.},
  author={Fotini Boufidou and Chryssoula K Nikolaou and Basil E Alevizos and Ioannis A. Liappas and George Christodoulou},
  journal={Journal of affective disorders},
  year={2004},
  volume={82 2},
  pages={
          309-13
        }
}
BACKGROUND Our knowledge concerning immune functioning in bipolar affective disorder (BAD) is limited, while lithium's immunomodulatory effects seem multiple and conflicting. Our aim was to evaluate cytokine production and lithium's effect on it in BAD patients, using ELISPOT technique as a sensitive tool. METHODS Cytokine (IL-2, IL-6, IL-10 and IFN-gamma) production from isolated peripheral blood lymphocytes (PBLs) was evaluated (ELISPOT technique) in 40 euthymic BAD patients under chronic… CONTINUE READING
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