Cytokine network in psoriasis revisited.
@article{MichalakStoma2011CytokineNI, title={Cytokine network in psoriasis revisited.}, author={Anna Michalak-Stoma and Aldona Pietrzak and Jacek Cezary Szepietowski and Anna M. Zalewska-Janowska and Tomasz Paszkowski and Graz̊yna Chodorowska}, journal={European cytokine network}, year={2011}, volume={22 4}, pages={ 160-8 } }
Psoriasis is a chronic genetically determined, erythemato-squamous disease associated with many comorbidities. Evidence from clinical studies and experimental models support the concept that psoriasis is a T cell-mediated inflammatory skin disease and T helper (Th) cells - Th1, Th17 and Th22 - play an important role in the pathogenesis. Th1 cytokines IFNγ, IL-2, as well as Th17 cytokines IL-17A, IL-17F, IL-22, IL-26, and TNFα (Th1 and Th17 cytokine) are increased in serum and lesional skin. IL…
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