Cytokine network analysis of cerebrospinal fluid in myalgic encephalomyelitis/chronic fatigue syndrome

@article{Hornig2016CytokineNA,
  title={Cytokine network analysis of cerebrospinal fluid in myalgic encephalomyelitis/chronic fatigue syndrome},
  author={Mady Hornig and G Gottschalk and D. L. Peterson and Konstance Kehl Knox and Andrew F. Schultz and Meredith L. Eddy and Xiaoyu Che and W. Ian Lipkin},
  journal={Molecular Psychiatry},
  year={2016},
  volume={21},
  pages={261-269}
}
Myalgic encephalomyelitis/chronic fatigue syndrome is an unexplained debilitating disorder that is frequently associated with cognitive and motor dysfunction. We analyzed cerebrospinal fluid from 32 cases, 40 subjects with multiple sclerosis and 19 normal subjects frequency-matched for age and sex using a 51-plex cytokine assay. Group-specific differences were found for the majority of analytes with an increase in cases of CCL11 (eotaxin), a chemokine involved in eosinophil recruitment. Network… CONTINUE READING
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