Cytokine mediated tissue fibrosis.

  title={Cytokine mediated tissue fibrosis.},
  author={Lee Anthony Borthwick and Thomas A. Wynn and Andrew J. Fisher},
  journal={Biochimica et biophysica acta},
  volume={1832 7},
Acute inflammation is a recognised part of normal wound healing. However, when inflammation fails to resolve and a chronic inflammatory response is established this process can become dysregulated resulting in pathological wound repair, accumulation of permanent fibrotic scar tissue at the site of injury and the failure to return the tissue to normal function. Fibrosis can affect any organ including the lung, skin, heart, kidney and liver and it is estimated that 45% of deaths in the western… CONTINUE READING
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