Cytokine-mediated communication by keratinocytes and Langerhans cells with dendritic epidermal T cells.

@article{Takashima1996CytokinemediatedCB,
  title={Cytokine-mediated communication by keratinocytes and Langerhans cells with dendritic epidermal T cells.},
  author={A. M. Takashima and Paul R. Bergstresser},
  journal={Seminars in immunology},
  year={1996},
  volume={8 6},
  pages={
          333-9
        }
}
Dendritic epidermal T cells (DETC) are skin-specific members of the epithelial gamma delta T-cell family that reside normally in murine epidermis. Recent studies indicate that certain cytokines (e.g. IL-2, IL-7 and IL-15) secreted by neighboring cells promote their residence and regulate their immune function. Conversely, DETC regulate the function of neighboring keratinocytes and Langerhans cells by elaborating other cytokines (e.g. interferon-gamma, keratinocyte growth factor and colony… CONTINUE READING

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