Cytokine-mediated communication between dendritic epidermal T cells and Langerhans cells. In vitro studies using cell lines.

@article{Yokota1996CytokinemediatedCB,
  title={Cytokine-mediated communication between dendritic epidermal T cells and Langerhans cells. In vitro studies using cell lines.},
  author={Koichi Yokota and Kiyoshi Ariizumi and Takashi Kitajima and Paul R. Bergstresser and Nancy E. Street and Akira Takashima},
  journal={Journal of immunology},
  year={1996},
  volume={157 4},
  pages={1529-37}
}
Murine epidermis contains two leukocyte populations: Langerhans cells (LC), which are APC of dendritic cell (DC) lineage, and dendritic epidermal T cells (DETC), which are members of the tissue-type gamma delta T cell family. Despite close physical approximation in vivo, the extent to which LC and DETC affect each other's function has remained unknown. We addressed this question using the long term DC line XS52 and the gamma delta T cell line 7-17, both of which were established from mouse… CONTINUE READING

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