Cytokine influence on simian immunodeficiency virus replication within primary macrophages. TNF-alpha, but not GMCSF, enhances viral replication on a per-cell basis.

Abstract

The control of HIV-1 or SIV replication within macrophages is probably influenced by a variety of viral and cellular factors. Of the cellular factors, the authors have studied cytokine influence on SIV replication in vitro utilizing simian alveolar macrophages and uncloned SIVmacMTV, a macrophage-tropic variant. The approach allowed quantification of viral… (More)

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@article{Walsh1991CytokineIO, title={Cytokine influence on simian immunodeficiency virus replication within primary macrophages. TNF-alpha, but not GMCSF, enhances viral replication on a per-cell basis.}, author={Dermot Walsh and Carly Horvath and A Hansen-Moosa and Jonathan Mackey and Priya Sehgal and Michael Daniel and Robert Desrosiers and Doron Ringler}, journal={The American journal of pathology}, year={1991}, volume={139 4}, pages={877-87} }