Cytokine-inducing macromolecular glycolipids from Enterococcus hirae: improved method for separation and analysis of its effects on cellular activation.

@article{Hashimoto2000CytokineinducingMG,
  title={Cytokine-inducing macromolecular glycolipids from Enterococcus hirae: improved method for separation and analysis of its effects on cellular activation.},
  author={Mamoru Hashimoto and Yasutada Imamura and Toshihiko Morichika and Kazue Arimoto and Osamu Takeuchi and Kazuya Takeda and Shizuo Akira and Kohji Aoyama and Tomohiro Tamura and Sachie Kotani and Yasuo Suda and Shoichi Kusumoto},
  journal={Biochemical and biophysical research communications},
  year={2000},
  volume={273 1},
  pages={164-9}
}
Previously, we showed that several minor macromolecular glycolipids accounting for less than 5% of the lipoteichoic acid (LTA) fraction from Enterococcus hirae ATCC 9790 possess cytokine-inducing activity, whereas the purified LTA does not. In other words, the immunobiological activity of the LTA fraction reported in the 1980s was not attributable to LTA… CONTINUE READING